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Job Title
Clinical Research Coordinator II
Academic Rank
Staff/Research Assistant
Department
Psychiatry
Authors
Hurley, Catherine; Lipschitz, Jessica M.; O’Neal, Mary; Pike, Chelsea
Principal Investigator
Dr. Katherine Burdick, PhD
Categories
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Background: Identifying factors related to migraine onset would allow patients to take prophylactic measures. Intense emotions are a potential factor affecting migraine onset. We aimed to explore the relationship between day-to-day experience of sadness, happiness, anxiety/stress, and interpersonal stress and migraine onset.
Methods: We recruited 30 adult women with episodic migraine to engage in a 12-week monitoring period answering daily questionnaires via mobile app, which addressed headache occurrence and triggers, emotional intensity and sleep. We conducted linear regressions to understand overall relationship between emotional intensity and migraine onset, and mixed effects models to explore the temporal relationship.
Results: Linear regressions were not significant. Mixed effects models showed emotion intensity and migraine onset were significantly associated for happiness (estimate = -0.081; p = 0.027), anxiety/stress (estimate = 0.060; p = 0.040), and interpersonal stress (estimate = 0.120; p = 0.0017), but not sadness (estimate = 0.025; p = 0.46).
Conclusions: Findings suggest high anxiety/stress and interpersonal stress predict onset of migraine next day. Similarly, low happiness levels predict onset of migraine next day. These relationships were not significant when assessed over time. These findings support the need for longitudinal research evaluating the temporal relationship between emotion and migraine.
Background: Identifying factors related to migraine onset would allow patients to take preventative measures. Intense emotions are a potential factor affecting migraine onset. We aimed to explore the relationship between day-to-day experience of sadness, happiness, anxiety/stress, and interpersonal stress and migraine onset.
Methods: We recruited 30 adult women with episodic migraine to engage in a 12-week monitoring period answering daily questionnaires via mobile app, which addressed headache occurrence and triggers, emotional intensity and sleep. We measured the correlation between emotional intensity and migraine onset over time, and the correlation between emotional intensity one day and migraine onset the next day.
Results: Correlations between migraine onset and emotional intensity over time were not statistically significant. Next day occurrence for emotion intensity and migraine onset were significantly associated for happiness, anxiety/stress, and interpersonal, but not sadness.
Conclusions: Findings suggest high anxiety/stress and interpersonal stress predict onset of migraine next day. Similarly, low happiness levels predict onset of migraine next day. These relationships were not significant when assessed over time. These findings support the need for long-term research evaluating the day-to-day relationship between emotion and migraine.
