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Chelsea Pike

Pronouns

She/Her/Hers

Job Title

Research Assistant

Academic Rank

Department

Psychiatry

Authors

Chelsea K. Pike, Caitlin Millett, Katherine E. Burdick, Jessica M. Lipschitz

Principal Investigator

Katherine E. Burdick

Research Category: Psychiatry/Mental Health

Tags

Relationship between indicators of suicidality and measures of loneliness and social support among adults with mood disorders

Scientific Abstract

Background: Mood disorders, including bipolar disorder (BD) and major depressive disorder (MDD), are risk factors for suicide. Identifying modifiable variables that relate to suicide in these populations may inform prevention strategies.

Methods: 130 adults with mood disorders (N=71 bipolar disorder and N=59 major depressive disorder) completed clinical interviews (Hamilton Depression Rating Scale, HAM-D; Structured Clinical Interview for DSM-5, SCID-5) and self-report measures of loneliness (UCLA Loneliness Scale) and social support (Interpersonal Support Evaluation List). Analyses explored relationships between current suicidal ideation, lifetime suicide attempts, loneliness, and social support.

Results: Those with current suicidal ideation (per the HAM-D) reported feeling significantly lonelier (F(1,127)=8.606, p=.004) and reported lower perceived social support (F(1,120)=5.997, p=.016) than those without current ideation. Controlling for depression severity (HAM-D), those with a lifetime suicide attempt (per SCID-5) were also significantly lonelier (F(1,124)=11.495, p<.001) and reported lower social support (F(1,117)=11.559, p<.001) than those without attempts.

Conclusions: These findings add to the literature supporting a meaningful clinical relationship between loneliness and indicators of suicidality. Interventions specifically focused on reducing loneliness and building social support may be important in this population. As this work was cross-sectional, future research should elucidate the direction of these relationships.

Lay Abstract

Background: Mood disorders, including bipolar disorder (BD) and major depressive disorder (MDD), are risk factors for suicide. Identifying modifiable variables that relate to suicide in these populations may inform prevention strategies.

Methods: 130 adults with mood disorders (N=71 bipolar disorder and N=59 major depressive disorder) completed clinical interviews (Hamilton Depression Rating Scale, HAM-D; Structured Clinical Interview for DSM-5, SCID-5) and self-report measures of loneliness (UCLA Loneliness Scale) and social support (Interpersonal Support Evaluation List). Analyses explored relationships between current suicidal ideation, lifetime suicide attempts, loneliness, and social support.

Results: Those with current suicidal ideation (per the HAM-D) reported feeling significantly lonelier and reported lower perceived social support than those without current ideation. Controlling for depression severity (HAM-D), those with a lifetime suicide attempt (per SCID-5) were also significantly lonelier and reported lower social support than those without attempts.

Conclusions: These findings add to the literature supporting a meaningful clinical relationship between loneliness and indicators of suicidality. Interventions specifically focused on reducing loneliness and building social support may be important in this population. As this work was cross-sectional, future research should elucidate the direction of this relationship.

Clinical Implications

Interventions to enhance social support and reduce loneliness may be warranted in patients at risk for suicide. Particular attention must be paid to loneliness in the context of distancing measures that continue to be common as the COVID-19 pandemic continues.