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Jun Bai Park Chang
Pronouns
He/Him/His
Job Title
Research Assistant II
Academic Rank
Department
Medicine
Authors
Jun Bai Park Chang, Michaël Desjardins, Lewis A. Novack, Amy C. Sherman, Andy Kim, Natalie Boutin, Lisa Mahanta, Xander Cerretani, Opeyemi Talabi-Oates, Adetoun Okenla, Elizabeth Sampson, Haley Schram, Karen Magsipoc, Kirsten Goodman, Lauren Donahue, Maureen MacGowan, Guohai Zhou, Ann E. Woolley, Stephen R. Walsh, Elizabeth W. Karlson, Lindsey R. Baden
Principal Investigator
Lindsey R. Baden
Research Category: COVID-19
Tags
In March 2020, a biorepository for samples from those infected with SARS-CoV-2 was developed at Brigham and Women’s Hospital (BWH). Participants were consented by the BWH Center for Clinical Investigation and processed and stored in conjunction with Mass General Brigham Biobank. We aim to assess if the population consented in the biorepository was representative of the population hospitalized with SARS-CoV-2 infection.
Demographics and clinical data were retrospectively collected from the electronic medical record on patients with COVID-19 admitted to BWH from March 7, 2020 to March 30, 2021.
A total of 1683 SARS-CoV-2 infected patients were admitted to BWH, and of these, 372 (22%) consented to join the biorepository. Consented patients identified as White and reported English as their primary language more than non-consented patients (56.2% vs. 46.3%, p=<0.001 and 83.1% vs. 71.2%, p=<0.001, respectively) and were younger (median age of 60 vs. 64, p=0.011). Fewer patients who consented to the biorepository were initially admitted to the ICU (15.3% vs. 22.5%, p=0.003). Both groups had a similar frequency of female patients (47.3% consented vs. 51.9% non-consented, p=0.13). Over 12,600 COVD-related samples have been distributed to 36 investigators since March 2020.
Further analysis is required to identify reasons behind these differences.
In March 2020 we started a biorepository for samples from people infected with SARS-CoV-2 at Brigham and Women’s Hospital (BWH). We wanted to know if the people who agreed to donate samples were representative of the overall population hospitalized with SARS-CoV-2 infection at BWH.
We collected demographics and clinical data from the electronic medical record on patients with COVID-19 admitted to BWH from March 7, 2020 to March 30, 2021.
A total of 1683 SARS-CoV-2 infected patients were admitted to BWH, and of these, 372 consented to join the biorepository. More participating patients identified as White, reported English as their primary language, and were younger than those who did not participate. Fewer patients who agreed to participate were initially admitted to the ICU. Both groups had a similar frequency of female patients.
Further analysis is required to identify the reasons behind these differences.
