Kutsev Ozyoruk, PhD

Pronouns

Rank

Institution

Harvard Medical School

Department

Pathology

Authors

Kutsev Bengisu Ozyoruk

Principal Investigator

Faisal Mahmood

Categories:

The Effect of Gender Inequality on Personalized Medicine: A Critical Review

Abstract

“Personalized medicine is an emerging field that aims to tailor medical treatments to individual patients based on their unique genetic, environmental, and lifestyle factors. However, the impact of gender inequality on the development and implementation of personalized medicine has received little attention. This review explores the ways in which gender inequality can affect personalized medicine, with a focus on three key areas: research, clinical practice, and policy.

First, we examine the impact of gender bias on research in personalized medicine. We discuss how the underrepresentation of women in clinical trials can limit the generalizability of findings and lead to ineffective or harmful treatments for women. We also highlight the importance of considering intersectionality – the interaction between gender and other social identities – in personalized medicine research.

Next, we discuss the effect of gender inequality on clinical practice. We explore how gender-based discrimination and stereotypes can influence the diagnosis, treatment, and management of diseases. We also examine how differences in health-seeking behaviors and social support networks can impact personalized medicine interventions.

Finally, we review the implications of gender inequality for personalized medicine policy. We discuss how policy decisions around funding, regulation, and reimbursement can affect the development and accessibility of personalized medicine, particularly for marginalized populations.

Overall, this review highlights the need for greater attention to gender inequality in personalized medicine. By recognizing and addressing the ways in which gender bias and discrimination can affect research, clinical practice, and policy, we can ensure that personalized medicine is truly personalized – that it takes into account the unique needs and experiences of all patients, regardless of their gender or other social identities.”

Research Context

This review explores the influence of gender inequality on personalized medicine in three key areas: research, clinical practice, and policy. Gender bias in research can limit the generalizability of findings and lead to ineffective or harmful treatments for women. The review emphasizes the importance of considering intersectionality in personalized medicine research. Gender-based discrimination and stereotypes can also affect the diagnosis, treatment, and management of diseases in clinical practice. Differences in health-seeking behaviors and social support networks can further influence personalized medicine interventions.

Lastly, the review discusses how gender inequality can impact personalized medicine policy decisions around funding, regulation, and reimbursement, particularly for marginalized populations. Addressing gender bias and discrimination in all areas of personalized medicine can ensure that it truly considers the unique needs and experiences of all patients, irrespective of their gender or other social identities. Therefore, it is crucial to recognize and address gender inequality in personalized medicine.