BRI Lung Research Day

Wednesday, October 30, 2024
2:30PM - 6:00PM

About the Day

Lung Research Day, hosted by the Brigham Research Institute’s (BRI) Lung Research Center, brings together pulmonary-related researchers and clinicians to highlight scientific achievements and promote cross-collaborative efforts. The event will feature short talks and a poster session with Brigham researchers, as well as a keynote address from Dr. John Reilly Jr.

Agenda

2:30-3:30 PM | Keynote Address: John Reilly, Jr, MD

Marshall A. Wolf Conference Center

3:30-4:30 PM | Featured Talks

Marshall A. Wolf Conference Center

4:40-5:10 PM | Poster Session – Round 1

Satter Atrium, Hale Building for Transformative Medicine

5:15-5:45 PM | Poster Session – Round 2

Satter Atrium, Hale Building for Transformative Medicine

5:45-6:00 PM | Closing Remarks

Satter Atrium, Hale Building for Transformative Medicine

Keynote Address

"The changing environment for academic medical centers and the implications for research"

John Reilly, Jr, MD

John Reilly, Jr, MD graduated from Dartmouth College and Harvard Medical School.  He trained in Internal Medicine and Pulmonary & Critical Care Medicine at Brigham and Women’s Hospital before joining the faculty there.  In 2008, he moved to Pittsburgh to join the Department of Medicine and became the department chairman in 2011.  He joined the CU School of Medicine in 2015 and served as Dean and Vice Chancellor for Health Affairs and as the President of CU Medicine, the faculty practice plan until 2024.  His research interests have focused on various clinical and translational studies related to chronic obstructive pulmonary disease.  In addition to his research publications, he has authored chapters on COPD in various major textbooks. 

Featured Talks

  • Remi Diesler, MD, Research Fellow, Medicine, Pulmonary and Critical Care: M2-Like Macrophage Polarization in Lymphangioleiomyomatosis (LAM)

     

  • Hadas Tamar Pahima, PhD, Research Fellow, Medicine, Allergy and Immunology: Cholesterol 25-Hydroxylase Play a Role in Recruiting Mast Cell Progenitors During Pulmonary Type 2 Inflammation

     

  • Anupama Singh, MD, Research Fellow, Surgery, Thoracic Surgery: Gait Speed as a Predictive Marker of Outcomes after Lung Resection

     

  • Miles Tran, BA, IS Programmer Analyst, Medicine, Rheumatology: Spatial Reconstruction of Interstitial Lung Disease

     

  • Jeong Yun, MD, MPH, Assistant Professor, Medicine, Channing Division of Network Medicine: Heterogeneity of Eosinophils in Chronic Obstructive Pulmonary Lung Disease

Poster Session Round 1

4:40PM - 5:10PM

  1. Antonio Arciniegas, MD
    Zinc Deficiency Contributes to Cell stretch-mediated lung injury
  2. Ameneh Asgari-Targhi, MSc, PhD
    Can Crowdsourced Annotations Improve AI-based Congestion Scoring For Bedside Lung Ultrasound?
  3. Kamakshi Bankoti, PhD
    BIK Increases Neuroendocrine Cell Numbers in Airway Epithelia to Affect Emphysema
  4. Nora Bensellam, MCA, BA
    Integration of Thermal Imaging and Checklist to Differentiate Cellulitis and Pseudocellulitis
  5. Thayse Bruggemann, PhD
    Eosinophil phenotypes are regulated by resolvin D2 during allergic lung inflammation
  6. Tiara Calhoun, MD
    Evaluating the process while testing the intervention: A process evaluation protocol for the BREATHE oxygen therapy randomized controlled trial in Kenya, Malawi, and Rwanda
  7. Claire Cutting, MD, MHS
    Interstitial Lung Abnormalities, Coronary Heart Disease, and Mortality
  8. Nam Dao, MD
    Validation Pipeline for Unstructured Data Extraction Using Artificial Intelligence
  9. David Deritei, MSc, PhD
    HHIP’s Dynamic Role in Epithelial Wound Healing Reveals a Potential Mechanism of COPD Susceptibility
  10. Zaid Elhusseini, PhD
    Genetic Determinants of Lung function Decline: A Multi-Level Analysis of Gene Expression
  11. Neda Esmaeili, MS, PhD
    The relationship between obesity and obstructive sleep apnea
  12. Vasile Foris, MD, PhD, MSc
    Variants of pulmonary hypertension associated genes in COPDGene
  13. Syed Moin Hassan, MD
    Leveraging Hybrid Natural Language Processing Techniques for Large-Scale Pulmonary Embolism Identification: Development and Validation of an Iterative and Novel Machine Learning and Rule-Based Pipeline
  14. Yichen Huang, MS
    Poverty may drive lung function disparities through epigenetic programming and age acceleration
  15. Narae Hwang, PhD
    Carbon Monoxide-induced Autophagy Enhances Human Mesenchymal Stromal Cell Function via Paracrine Actions in Murine Polymicrobial Sepsis
  16. Shelsey Johnson, MD
    Cluster analysis identifies novel computed tomography imaging-based phenotypes of pulmonary hypertension associated with chronic obstructive pulmonary disease (COPD-PH)
  17. Megha Kalia, PhD
    Self-Supervised Trackerless Navigation for Bronchoscopy with CT Geometry Prior
  18. Sean Kalra, MD
    The Association of a Polygenic Risk Score for Idiopathic Pulmonary Fibrosis with Transplant Free Survival in Biobank Cohorts
  19. Hassan Khalil, MD
    Circulating Tumor DNA Testing After Curative-intent Treatment for Lung Cancer
  20. Fei Li, MD, PhD
    Coordination of alanine synthesis and uptake contributes to fibroblast activation in pulmonary fibrosis
  21. Hao Li, MD
    Residual Viable Tumor Percentage of the Primary Tumor is an Independent Risk Factor for Lung Cancer Recurrence after Neoadjuvant Immunotherapy
  22. Camila Lopes-Ramos, PhD
    X Chromosome Methylation Patterns and Sex-Dosage Imbalance: Implications for COPD Susceptibility and Severity
  23. Kevin S. Ma, MD
    Safety and Effectiveness of Dupilumab in Patients with Chronic Obstructive Pulmonary Disease: A Target Trial Emulation

Poster Session Round 2

5:15PM - 5:45PM

  1. Cassidy Mays, BS
    Mesenchymal Stem Cells Enhance the Immune Response to Improve Outcomes in a Neonatal Model of Sepsis
  2. Zerihun Negasi, PhD
    Noxa Increases Immunoproteasomal Activity to Block the Development of COPD
  3. Nicoletta Ninkovic, MSc, PhD
    A novel population of CD8 memory T cells protects lung after skin vaccination
  4. Bonnie Patchen, PhD, RD
    Intersections Of Omega-3 Fatty Acids, DNA Methylation And Lung Function: A Nutritional Epigenetic Study In The Genetic Epidemiology Of COPD Study
  5. Fatemehsadat Pezeshkan, MD
    Tailored Approaches: Decision Support Model for Predicting Complete Response to neoadjuvant treatment in Stage III N2 Lung Cancer
  6. Eleanor Phillips, MD
    Frailty Associates with Respiratory Exacerbations and Mortality in the COPDGene Study
  7. Carrie Pistenmaa, MD, MS
    Combined CT Vascular Risk Assessment and FEV1 Decline in Smokers with and without COPD
  8. Nicole Prince, PhD
    A Network Approach to Characterize the Role of Early Life Protein Profiles in Childhood Respiratory Diseases
  9. Mizanur Rahman, PhD
    Importance of MUTYH in Chronic Obstructive Pulmonary Disease Discovered by Genome-wide Association Studies and Quantitative Traits in Airway Epithelia
  10. Aldric Rosario, PhD
    Metabolomic Profiling Reveals Distinct and Common Biological Pathways in COPD and IPF
  11. Jonathan Rose, MD, MS
    Proteins Biomarkers of Interstitial Lung Abnormalities in Relatives of Patients with Pulmonary Fibrosis
  12. Ethan Sam
    A Nanoparticle Platform for Effective Pulmonary Delivery of Biologics
  13. Rizza Santos, BA
    Gene signature for MCTC activation shown through transcriptome analysis of MCTCs in CRSwNP
  14. Woei-Yuh Saw, PhD
    Loss of Y chromosome associates with lung function decline in men with a history of smoking
  15. Anupama Singh, MD
    Pictorial Fit Frail Scale and Frailty in Lung Resection Patients
  16. Jada Suber, PhD
    Evaluating allergen-mediated human MC subset sensitivity using a novel MCT in-vitro model
  17. Abhijeet Thakur, PhD
    Diverse Responses of Pulmonary Endothelial Cell Subpopulations in Neonatal Lung Injury
  18. Carla Vega, MD
    Assessing the Adoption of Combined Immunotherapy and Chemotherapy in Eligible Patients with Non-Small Cell Lung Cancer
  19. Ke Xu, MD, PhD
    An Observation Study of EBUS Procedures at Brigham and Women’s Hospital
  20. Rongguang Xu, PhD
    Buckling forces and the wavy folds between pleural epithelial cells
  21. Hanyi Yang, BS
    Serum fatty-acid binding protein (FABP4) protein is associated with lung function in asthma: insights into the pathogenesis of obesity-related asthma
  22. Daniel Zapata, MD
    Continuous Bilateral Parasternal Nerve Blockade Following Allograft Lung Transplantation: A Retrospective Exploratory Analysis

Room Directions

Marshall A. Wolf Conference Center

3rd floor, Hale Building for Transformative Medicine (Hale BTM):

From 60 Fenwood Road: Enter at 60 Fenwood Rd lobby entrance.

STAIRS:

Take the lobby staircase to the 2nd floor. Walk past the balcony overlooking the atrium and take the stairs on the left (Stair 2) to the 3rd floor. Once on the 3rd floor, exit the stairwell and take a right. The room is to your right through the double glass door, straight ahead.

ELEVATOR:

Take S Elevator to 3rd floor. Take a right out of the elevator. The room is past the stairwell, on your right through the double glass doors.

 

Satter Atrium (previously called Hale Cafe Atrium)

1st floor, Hale Building for Transformative Medicine (Hale BTM):

From 60 Fenwood Road: Coming from Marshall A. Wolf Conference Center.

STAIRS

Coming from Marshall A. Wolf Conference Center, exit through the double glass doors and take the stairwell, which is located on the left, to the 1st Floor, and the Satter Atrium is located in the open space to your right.

ELEVATOR:

Take the S elevators (or employee elevators if you have access) to the 1st floor, and the atrium will be on your right.