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Previous studies suggest that the median preoptic nucleus (MnPO) plays an important role in regulating the wake-sleep cycle and in particular homeostatic sleep drive. However, the precise cellular phenotypes, targets and central mechanisms by which the MnPO neurons regulate the wake-sleep cycle remain unknown. Both excitatory and inhibitory MnPO neurons innervate brain regions implicated in sleep promotion and maintenance, suggesting that both cell types may participate on sleep control. Using genetically-targeted approaches, we investigated the role of the MnPO GABAergic (MnPOVgat) and glutamatergic (MnPOVglut2) neurons in modulating the wake-sleep behavior.
10:00 – 11:30 AM ET
HMS DSM Annual Faculty Meeting
10:00 – 11:30 AM ET
Mary A. Carskadon, PhD Introductory Meeting with HMS DSM Trainees
12:00 – 1:15 PM ET
Division of Sleep Medicine Annual Prize Lecture by Mary A. Carskadon, PhD
1:15 – 1:30 PM ET
Awarding of 2020 Harvard Medical School Division of Sleep Medicine Prize to Mary A. Carskadon, PhD
3:00 – 4:30 PM ET
Poster Session
4:30 – 5:30 PM ET
Reception
6:00 – 7:00 PM ET
Evening Public Lecture by Mary A. Carskadon, PhD
“Changes in Sleep Biology Create a Perfect Storm Affecting Teen Health and Well-Being”