There is a misconception that ischemic heart disease (IHD) mostly affects males in high-income countries. However, about 80% of CVD mortalities predominantly occur in LMICs, and IHD remains a major cause of death globally. Even less is known about the sex burden of IHD in females. Our work explores the trends in IHD in the most populous LMICs and describes trends in mortality rates from IHD among females.
We highlight that the burden of IHD is increasing in LMICs. While the age standardized mortality rate is improving in most countries, the improvement is not consistent across time, and is starting to reverse among females, with a slower decline in many countries than in males. The proportion of deaths amongst females from IHD doubled from 6% in 1990 to 13% in 2019. Sex-specific interventions are needed in LMICs to address the rising prevalence of IHD in females.