Genomics and Bioinformatics Hub: A new resource for bioinformatics research, services, and training at Brigham

Xianjun Dong, PhD
Department of Neurology
Division of Basic Neuroscience Research
Poster Overview

Following the booming of sequencing technology and digitalized medical information, demand in bioinformatics is also increasing dramatically. With support from the NeuroTechnology Studio, we are now launching a new program, the Genomics and Bioinformatics Hub, in order to meet the needs of bioinformatics in the research community at Brigham and Women’s Hospital. With the new hub, we aim to bridge the gap between lab and computational scientists to their mutual benefit, and to support cutting-edge, highly quantitative biomedical research. The program will create and maintain computational tools and biomedical data sources, and will support studies in basic, translational and clinical neurosciences using available or in-house computational techniques. In addition, the program provides collaboration opportunities and bioinformatics services for research scientists in BWH, with a focus on brain diseases and fundamental neuroscience research. At this stage, the program will primarily provide ‘omics sequencing data analysis service, including genomics, transcriptomics, epigenomics etc. While our primary goal is to support the BWH neuroscience community, our service is available at the same rate ($150/hr) to other Brigham researchers. For more details, please contact us at bioinformatics@bwh.harvard.edu or visit our website: http://bioinformatics.bwh.harvard.edu.

Scientific Abstract

The demand of bioinformatics is increasing along with the widely applied next-generation sequencing technologies and digitized medical information. With support from the BWH NeuroTechnology Studio, we are now turning the Bioinformatics Club to a more formal program to meet the needs of bioinformatics in the research community at Brigham and Women’s Hospital. With the new Genomics and Bioinformatics Hub, we aim to bridge the gap between lab and computational scientists to their mutual benefit, and to support cutting-edge, highly quantitative biomedical research. The program will create and maintain bioinformatics tools and databases, and provides collaboration opportunities and bioinformatics services for research scientists in BWH, with a focus on brain diseases and fundamental neuroscience research. At this stage, the program will primarily provide next-generation sequencing data analysis service, including but not limited to single-cell and bulk tissue RNA-seq, ATAC-seq, genotyping, whole-genome/-exome sequencing, ChIP-seq, CAGE etc. While our primary goal is to support the BWH neuroscience community, our service is available at the same rate ($150/hr) to other Brigham researchers. In addition, we will also provide bioinformatics training and sequencing services (Nextseq and 10x Genomics). For more details, please contact us at bioinformatics@bwh.harvard.edu or visit our website: http://bioinformatics.bwh.harvard.edu.

Clinical Implications
The newly launched Genomics and Bioinformatics Hub at Brigham and Women’s Hospital will provide collaborative research, service, and training in bioinformatics to the community. It will meet the gap between increasing volume of next-generation sequencing data and unsolved biomedical questions.
Research Areas
Authors
Xianjun Dong, Alexander Lukyanov, Xiaoqi Li, Clemens Scherzer, Charles Jennings, Dennis Selkoe
Principal Investigator
Xianjun Dong

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